METOBOLIK SINDROMDA XOLESTERIN METABOLIZMINING O‘ZGARISHI
Keywords:
metabolik sindrom, dislipidemiya, xolesterin metabolizmi, LDL, HDL, triglitserid, atherogenez, small dense LDL.Abstract
Ushbu maqola Metabolik sindrom (MS) holatida xolesterin va lipid metabolizmining o‘zgarishlari, ya’ni dislipidemiya shakllanishi, lipoprotein fraksiyalarining qayta taqsimlanishi (triglitseridlar, HDL, LDL, ayniqsa kichik zichlikli LDL), shuningdek, bu o‘zgarishlarning aterogenez va yurak-qon tomir kasalliklari (YQTK) xavfi bilan bogʻliqligi hamda patofizyologik mexanizmlar — yallig‘lanish, oksidlov, reverse xolesterin transporti buzilishi orqali qanday namoyon bo‘lishini tahlil qiladi. Mavjud adabiyotlar tizimli sharhi va statistik ma’lumotlar asosida sintez qilindi. Maqola klinik va profilaktik tavsiyalar ham beradi.
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